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Elizabeth A Walker Selected Research

galactose-6-phosphate dehydrogenase

10/2008Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency.
3/2008Deletion of hexose-6-phosphate dehydrogenase activates the unfolded protein response pathway and induces skeletal myopathy.
12/2007Hypoglycemia with enhanced hepatic glycogen synthesis in recombinant mice lacking hexose-6-phosphate dehydrogenase.
3/2006Hexose-6-phosphate dehydrogenase knock-out mice lack 11 beta-hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation.
6/2005Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1.
10/200411beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response.
8/2003Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency.

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Elizabeth A Walker Research Topics

Disease

12Hearing Loss (Hearing Impairment)
03/2022 - 01/2013
6Type 2 Diabetes Mellitus (MODY)
10/2018 - 02/2002
5Obesity
10/2018 - 03/2002
5Insulin Resistance
07/2012 - 04/2005
5Metabolic Syndrome (Dysmetabolic Syndrome X)
07/2012 - 10/2004
5Cortisone reductase deficiency
03/2011 - 08/2003
3Infections
01/2022 - 10/2019
3Abdominal Obesity
07/2012 - 11/2002
3Muscular Diseases (Myopathy)
04/2011 - 03/2008
3Hypoglycemia (Reactive Hypoglycemia)
01/2011 - 12/2007
2Otitis Media with Effusion
01/2022 - 01/2022
2Nasal Obstruction
01/2022 - 01/2022
2Otitis Media
01/2022 - 01/2022
2Hypertension (High Blood Pressure)
02/2019 - 08/2003
2Hemorrhage
01/2019 - 08/2017
2Glucose Intolerance
07/2012 - 09/2006
2Inflammation (Inflammations)
09/2011 - 01/2010
2Cushing Syndrome
01/2011 - 03/2002
2Weight Loss (Weight Reduction)
12/2010 - 02/2002
2Pseudotumor Cerebri (Idiopathic Intracranial Hypertension)
12/2010 - 02/2010
1Language Development Disorders (Semantic-Pragmatic Disorder)
03/2022
1Otitis
01/2022
1Bilateral Hearing Loss
01/2020
1Sepsis (Septicemia)
10/2019
1Meningitis
10/2019
1Thrombocytopenia (Thrombopenia)
01/2019
1Deafness (Deaf Mutism)
01/2019
1Gestational Diabetes (Gestational Diabetes Mellitus)
10/2018
1Prediabetic State (Prediabetes)
10/2018
1Thrombosis (Thrombus)
08/2017
1Cardiovascular Diseases (Cardiovascular Disease)
08/2017
1Chronic Kidney Failure (Chronic Renal Failure)
08/2017
1Keratitis
01/2014
1Atrophy
07/2013
1Body Weight (Weight, Body)
07/2012
1Oculocutaneous albinism type 2
09/2011
1Oculocutaneous Albinism (Albinism, Yellow Mutant)
09/2011
1Muscular Atrophy (Muscle Atrophy)
01/2011
1Intracranial Hypertension
12/2010
1Sensorineural Hearing Loss
10/2010
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
02/2010
1Multiple Sclerosis
02/2010
1Graves Ophthalmopathy
01/2010
1Autoimmune Diseases (Autoimmune Disease)
01/2010
1Weight Gain
12/2007
1Hypertrophy
02/2007
1Hyperplasia
02/2007
1Glaucoma
10/2004
1Osteoporosis
10/2004

Drug/Important Bio-Agent (IBA)

1111-beta-Hydroxysteroid Dehydrogenase Type 1IBA
03/2011 - 01/2002
9GlucocorticoidsIBA
07/2012 - 03/2002
8Hydrocortisone (Cortisol)FDA LinkGeneric
03/2011 - 03/2002
7Glucose (Dextrose)FDA LinkGeneric
07/2012 - 02/2002
7galactose-6-phosphate dehydrogenaseIBA
10/2008 - 08/2003
4AndrogensIBA
03/2011 - 08/2003
4CortisoneFDA Link
12/2010 - 08/2003
4Oxidoreductases (Dehydrogenase)IBA
12/2010 - 06/2004
3Metformin (Glucophage)FDA LinkGeneric
10/2018 - 02/2002
3Biomarkers (Surrogate Marker)IBA
01/2014 - 10/2008
3EnzymesIBA
06/2005 - 01/2003
2LipidsIBA
02/2019 - 07/2012
2GlycogenIBA
01/2011 - 03/2008
2SteroidsIBA
10/2008 - 06/2004
2Adrenocorticotropic Hormone (ACTH)FDA Link
10/2008 - 08/2003
2Insulin (Novolin)FDA Link
03/2008 - 12/2007
2CorticosteroneIBA
03/2008 - 12/2007
211-beta-Hydroxysteroid Dehydrogenase Type 2 (11 beta-Hydroxysteroid Dehydrogenase Type 2)IBA
08/2003 - 01/2002
1Anti-Bacterial Agents (Antibiotics)IBA
01/2022
1Virulence Factors (Pathogenicity Factors)IBA
10/2019
1Glutathione (Reduced Glutathione)IBA
10/2019
1Heparin (Liquaemin)FDA LinkGeneric
01/2019
1bivalirudin (Angiomax)FDA Link
01/2019
1BiguanidesIBA
10/2018
1omega-Chloroacetophenone (Mace)IBA
08/2017
1Tirofiban (Aggrastat)FDA Link
08/2017
1CollagenIBA
07/2013
1Triglycerides (Triacylglycerol)IBA
07/2012
1Amyloid (Amyloid Fibrils)IBA
09/2011
1Peptides (Polypeptides)IBA
09/2011
1AngiopoietinsIBA
09/2011
1Adrenal Cortex Hormones (Corticosteroids)IBA
12/2010
111-beta-Hydroxysteroid Dehydrogenases (11beta Hydroxysteroid Dehydrogenase)IBA
01/2010
1Troleandomycin (TAO)FDA Link
01/2010
1Liver GlycogenIBA
12/2007
1Troglitazone (Rezulin)FDA Link
04/2005
1NADP (NADPH)IBA
10/2004

Therapy/Procedure

9Hearing Aids (Hearing Aid)
03/2022 - 01/2013
3Cochlear Implants (Cochlear Implant)
01/2019 - 10/2010
2Therapeutics
01/2022 - 08/2017
2Middle Ear Ventilation (Tympanostomy)
01/2022 - 01/2022
2Adenoidectomy
01/2022 - 01/2022
2Electrodes (Electrode)
01/2019 - 10/2010
1Perioperative Period
01/2022
1Ear Protective Devices (Earplug)
01/2022
1Self Medication
02/2019
1Renal Dialysis (Hemodialysis)
08/2017
1Stents
08/2017
1Glycemic Control
11/2012
1Cochlear Implantation
10/2010
1Surgical Amputation (Amputations)
05/2010